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A highway bridge has reportedly collapsed in the US state of Washington, sending at least two cars with people inside into the water.

The Interstate 5 Skagit River Bridge, about 100 kilometres north of Seattle, collapsed on Thursday evening, KIRO-TV reported.

Rescue teams are currently searching the river for survivors.

Both the north-bound and south-bound lanes of the bridge dropped into the river about 7pm, Washington State Patrol trooper Mark Francis wrote in a tweet.

He said several cars were on the bridge when it collapsed, and they were now in the water.

It was unclear whether anyone was injured or killed in the collapse.